We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cardiomyopathy, pericarditis and myocarditis in a population-based cohort of inpatients with coeliac disease.
- Authors
Elfström, P.; Hamsten, A.; Montgomery, S. M.; Ekbom, A.; Ludvigsson, J. F.
- Abstract
Objectives: We investigated the risk of myocarditis, cardiomyopathy, and pericarditis in patients with celiac disease (CD) from a general population cohort. Subjects and methods: Through the Swedish national registers we identified 9363 children and 4969 adults with a diagnosis of CD (1964–2003). These individuals were matched with upto five reference individuals for age, sex, calendar year and county ( n = 69 851). Cox regression estimated hazard ratios (HRs) for later heart disease. Main outcome measures: Myocarditis, cardiomyopathy (any or dilated), and pericarditis defined according to relevant international classification of disease codes in the Swedish national inpatient register. Results: Celiac disease diagnosed in childhood was not associated with later myocarditis (HR = 0.2; 95% CI = 0.0–1.5), cardiomyopathy of any type (HR = 0.8; 95% CI = 0.2–3.7), or pericarditis (HR = 0.4; 95% CI = 0.1–1.9). Restricting our analyses to adulthood CD and heart disease diagnosed from 1987 and onwards in departments of cardiology/internal medicine, we found no association between CD and later myocarditis (HR = 2.1; 95% CI = 0.4–11.7), dilated cardiomyopathy (HR = 1.7; 95% CI = 0.4–6.5) or pericarditis (HR = 1.5; 95% CI = 0.5–4.0). Conclusion: This study found no association between CD, later myocarditis, cardiomyopathy or pericarditis.
- Subjects
CELIAC disease; PATIENTS; CARDIOMYOPATHIES; PERICARDITIS; MYOCARDITIS; AUTOIMMUNITY
- Publication
Journal of Internal Medicine, 2007, Vol 262, Issue 5, p545
- ISSN
0954-6820
- Publication type
Article
- DOI
10.1111/j.1365-2796.2007.01843.x