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- Title
Muscle Potassium and Potassium Losses During Hypokinesia in Healthy Subjects.
- Authors
Federenko, Yuri; Deogenov, Viktor; Kakuris, Kostas; Yerullis, Kostas
- Abstract
Hypokinesia (HK) induces electrolyte losses in electrolyte-deficient tissue, yet the mechanisms of electrolyte losses in electrolyte-deficient tissue remain unknown. Mechanisms of electrolyte deposition could be involved. To determine the effect of prolonged HK on potassium (K) deposition were measured muscle K content and K losses. Studies were conducted on 20 physically healthy male volunteers during 30 days pre-experimental period and 364 days experimental period. Subjects were equally divided into two groups: control subjects (CS) and experimental subjects (ES). The CS group was run average distances of 9.8 ± 1.7 km day and the ES group was walked average distances of 2.7 ± 0.6 km day. Muscle K content decreased ( p < 0.05) and plasma K concentration, and K losses in urine and feces increased ( p < 0.05) in the ES group compared to their pre-experimental level and the values in their respective CS group. Muscle K content, plasma K level, and urine and fecal K losses did not show any changes in the CS group compared to their pre-experimental values. The conclusion was that K losses in K-deficient muscle of healthy subjects could have been attributable to the less efficient K deposition inherently to prolonged HK.
- Subjects
MUSCLE physiology; POTASSIUM; HYPOKINESIA; POTASSIUM deficiency diseases; HYPOVOLEMIC anemia
- Publication
Biological Trace Element Research, 2011, Vol 143, Issue 2, p668
- ISSN
0163-4984
- Publication type
Article
- DOI
10.1007/s12011-010-8900-1