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- Title
A case of apoplectic lymphocytic hypophysitis complicated by polymyalgia rheumatica.
- Authors
Tanaka, Yasuko; Hirao, Tomohito; Tsutsumi, Keisuke; Miyashita, Taiichiro; Izumi, Yasumori; Mihara, Yumi; Ito, Masahiro; Baba, Hiroshi; Migita, Kiysohi
- Abstract
A case of apoplectic lymphocytic hypophysitis complicated by polymyalgia rheumatica (PMA) is described. A 72-year-old man was admitted to our hospital due to severe headache. Two months prior to admission, the patients had exhibited recent-onset stiffness and myalgia of shoulder and pelvic girdle that was compatible with PMR. Magnetic resonance imaging revealed a mass lesion in the pituitary fossa with focal hemorrhage. Endocrinologic studies demonstrated hypopituitarism. The headache and myalgia were improving with corticosteroid treatment; however, a trans-sphenoidal surgery was performed due to visual field loss. A white-colored mass was resected, and histologic examination showed diffuse infiltration of lymphocytes and plasma cells consistent with lymphocytic hypophysitis. Post-operatively, the headache and visual field loss resolved completely. This is the first documented case of apoplectic lymphocytic hypophysitis complicating PMR, and a possible mechanism for this rare association was discussed.
- Subjects
CASE studies; POLYMYALGIA rheumatica; LYMPHOCYTIC leukemia; MYALGIA; MUSCLE diseases; LYMPHOID tissue
- Publication
Rheumatology International, 2013, Vol 33, Issue 1, p215
- ISSN
0172-8172
- Publication type
Report
- DOI
10.1007/s00296-010-1535-x