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- Title
Non-Hodgkin's lymphoma following treatment with etanercept in ankylosing spondylitis.
- Authors
Aksu, Kenan; Cagirgan, Seckin; Ozsan, Nazan; Keser, Gokhan; Sahin, Fahri
- Abstract
Anti-TNF drugs may increase lymphoma risk in autoimmune rheumatic diseases, such as rheumatoid arthritis, but there have been no reports stating increased risk of lymphoma in ankylosing spondylitis (AS). Before 2 years, we had presented a case with AS developing Hodgkin's lymphoma following 6 months of etanercept treatment. Hereby, we present another case with AS developing non-Hodgkin's lymphoma (NHL), subsequent to 11 months of etanercept treatment. Pathological analysis revealed diffuse large B cell NHL. Although this is a report of a single case, cautious use of anti-TNF drugs is strongly recommended as they might cause lymphoma development even in AS.
- Subjects
CASE studies; LYMPHOMA treatment; ETANERCEPT; ANKYLOSING spondylitis; RHEUMATOID arthritis; PATHOLOGY; B cell differentiation
- Publication
Rheumatology International, 2011, Vol 31, Issue 12, p1645
- ISSN
0172-8172
- Publication type
Report
- DOI
10.1007/s00296-009-1265-0