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The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis.
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- Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 12, p. 3137, doi. 10.1007/s00432-020-03424-2
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- Article
The role of dietary phytochemicals in the carcinogenesis via the modulation of miRNA expression.
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- Journal of Cancer Research & Clinical Oncology, 2019, v. 145, n. 7, p. 1665, doi. 10.1007/s00432-019-02940-0
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- Article
Controlling metastatic cancer: the role of phytochemicals in cell signaling.
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- Journal of Cancer Research & Clinical Oncology, 2019, v. 145, n. 5, p. 1087, doi. 10.1007/s00432-019-02892-5
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- Article
PCNB exposure during early embryogenic development induces developmental delay and teratogenicity by altering the gene expression in Xenopus laevis.
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- Environmental Toxicology, 2023, v. 38, n. 1, p. 216, doi. 10.1002/tox.23679
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- Article
BAI, a novel Cdk inhibitor, enhances farnesyltransferase inhibitor LB42708-mediated apoptosis in renal carcinoma cells through the downregulation of Bcl-2 and c-FLIP (L).
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- International Journal of Oncology, 2014, v. 45, n. 4, p. 1680, doi. 10.3892/ijo.2014.2534
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- Article
Immunohistochemical analysis for histopathological subtypes in pediatric medulloblastomas.
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- Pathology International, 2003, v. 53, n. 2, p. 67, doi. 10.1046/j.1440-1827.2003.01444.x
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- Article
Fisetin Attenuated Oxidative Stress-Induced Cellular Damage in ARPE-19 Human Retinal Pigment Epithelial Cells Through Nrf2-Mediated Activation of Heme Oxygenase-1.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.927898
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USP41 Enhances Epithelial–Mesenchymal Transition of Breast Cancer Cells through Snail Stabilization.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1693, doi. 10.3390/ijms24021693
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- Article
4-O-Methylascochlorin-Mediated BNIP-3 Expression Controls the Balance of Apoptosis and Autophagy in Cervical Carcinoma Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15138, doi. 10.3390/ijms232315138
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- Article
Lucanthone, Autophagy Inhibitor, Enhances the Apoptotic Effects of TRAIL through miR-216a-5p-Mediated DR5 Upregulation and DUB3-Mediated Mcl-1 Downregulation.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 17, doi. 10.3390/ijms23010017
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- Article
Inhibition of BMI-1 Induces Apoptosis through Downregulation of DUB3-Mediated Mcl-1 Stabilization.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 10107, doi. 10.3390/ijms221810107
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Farrerol Induces Cancer Cell Death via ERK Activation in SKOV3 Cells and Attenuates TNF-α-Mediated Lipolysis.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9400, doi. 10.3390/ijms22179400
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Cyclin-Dependent Kinase Inhibitor BMI-1026 Induces Apoptosis by Downregulating Mcl-1 (L) and c-FLIP (L) and Inactivating p-Akt in Human Renal Carcinoma Cells.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 4268, doi. 10.3390/ijms22084268
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- Article
Anti-Inflammatory Effects of the Novel PIM Kinase Inhibitor KMU-470 in RAW 264.7 Cells through the TLR4-NF-κB-NLRP3 Pathway.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 5138, doi. 10.3390/ijms21145138
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- Article
Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 13, p. 3253, doi. 10.3390/ijms20133253
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Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma In Vivo and In Vitro.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1749, doi. 10.3390/ijms20071749
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- Article
Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3280, doi. 10.3390/ijms19103280
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- Article
Corosolic Acid Induces Non-Apoptotic Cell Death through Generation of Lipid Reactive Oxygen Species Production in Human Renal Carcinoma Caki Cells.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 5, p. 1309, doi. 10.3390/ijms19051309
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- Article
Volasertib Enhances Sensitivity to TRAIL in Renal Carcinoma Caki Cells through Downregulation of c-FLIP Expression.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 12, p. 2568, doi. 10.3390/ijms18122568
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Morin, a Flavonoid from Moraceae, Induces Apoptosis by Induction of BAD Protein in Human Leukemic Cells.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 1, p. 645, doi. 10.3390/ijms16010645
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- Article
Aberrant p16<sup>INK4A</sup> RNA transcripts expressed in hepatocellular carcinoma cell lines regulate pRb phosphorylation by binding with CDK4, resulting in delayed cell cycle progression.
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- Liver International, 2003, v. 23, n. 3, p. 194, doi. 10.1034/j.1600-0676.2003.00821.x
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- Article
Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention.
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- Clinical & Experimental Medicine, 2020, v. 20, n. 2, p. 173, doi. 10.1007/s10238-020-00611-w
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- Article
An essential microRNA maturing microprocessor complex component DGCR8 is up-regulated in colorectal carcinomas.
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- Clinical & Experimental Medicine, 2014, v. 14, n. 3, p. 331, doi. 10.1007/s10238-013-0243-8
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- Article
Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling.
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- Experimental & Molecular Medicine EMM, 2024, v. 56, n. 2, p. 383, doi. 10.1038/s12276-024-01163-9
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- Article
Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells.
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- Scientific Reports, 2016, p. 22921, doi. 10.1038/srep22921
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- Article
Galangin sensitizes TRAIL-induced apoptosis through down-regulation of anti-apoptotic proteins in renal carcinoma Caki cells.
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- Scientific Reports, 2016, p. 18642, doi. 10.1038/srep18642
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- Article
(–)-EPIGALLOCATECHIN GALLATE ATTENUATES GLUTAMATE-INDUCED CYTOTOXICITY VIA INTRACELLULAR CA<sup>2+</sup> MODULATION IN PC12 CELLS.
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- Clinical & Experimental Pharmacology & Physiology, 2004, v. 31, n. 8, p. 530, doi. 10.1111/j.1440-1681.2004.04044.x
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- Article
Curcumin Significantly Enhances Dual PI3K/Akt and mTOR Inhibitor NVP-BEZ235-Induced Apoptosis in Human Renal Carcinoma Caki Cells through Down-Regulation of p53-Dependent Bcl-2 Expression and Inhibition of Mcl-1 Protein Stability.
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- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095588
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Elucidation for modulation of death receptor (DR) 5 to strengthen apoptotic signals in cancer cells.
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- Archives of Pharmacal Research, 2019, v. 42, n. 1, p. 88, doi. 10.1007/s12272-018-01103-y
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- Article
Chalcone-templated Hsp90 inhibitors and their effects on gefitinib resistance in non-small cell lung cancer (NSCLC).
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- Archives of Pharmacal Research, 2017, v. 40, n. 1, p. 96, doi. 10.1007/s12272-016-0848-z
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- Article
Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells.
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- Archives of Pharmacal Research, 2008, v. 31, n. 10, p. 1303, doi. 10.1007/s12272-001-2110-5
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- Article
Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats.
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- Evidence-based Complementary & Alternative Medicine (eCAM), 2009, v. 6, n. 2, p. 195, doi. 10.1093/ecam/nem078
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- Article
Overexpression of Par-4 sensitizes TRAIL-induced apoptosis via inactivation of NF-κB and Akt signaling pathways in renal cancer cells.
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- Journal of Cellular Biochemistry, 2010, v. 109, n. 5, p. 885, doi. 10.1002/jcb.22504
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- Article
Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIP.
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- Journal of Cellular Biochemistry, 2008, v. 105, n. 6, p. 1386, doi. 10.1002/jcb.21958
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- Article
Overexpression of cFLIPs inhibits oxaliplatin-mediated apoptosis through enhanced XIAP stability and Akt activation in human renal cancer cells.
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- Journal of Cellular Biochemistry, 2008, v. 105, n. 4, p. 971, doi. 10.1002/jcb.21905
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- Article
Sanguinarine-induced apoptosis: Generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL.
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- Journal of Cellular Biochemistry, 2008, v. 104, n. 3, p. 895, doi. 10.1002/jcb.21672
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- Publication type:
- Article
Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells.
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- Journal of Cellular Biochemistry, 2008, v. 103, n. 2, p. 358, doi. 10.1002/jcb.21642
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- Article
Expression of cyclin D3 through Sp1 sites by histone deacetylase inhibitors is mediated with protein kinase C-δ (PKC-δ) signal pathway.
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- Journal of Cellular Biochemistry, 2007, v. 101, n. 4, p. 987, doi. 10.1002/jcb.21316
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- Publication type:
- Article
Glucocorticoid receptor antagonist sensitizes TRAIL-induced apoptosis in renal carcinoma cells through up-regulation of DR5 and down-regulation of c-FLIP(L) and Bcl-2.
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- Journal of Molecular Medicine, 2012, v. 90, n. 3, p. 309, doi. 10.1007/s00109-011-0821-8
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- Article
Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 12, p. 838, doi. 10.3390/biom9120838
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- Article
DNA Methylation Status in Cancer Disease: Modulations by Plant-Derived Natural Compounds and Dietary Interventions.
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- Biomolecules (2218-273X), 2019, v. 9, n. 7, p. 289, doi. 10.3390/biom9070289
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- Article
Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC d signal transduction.
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- Oncogene, 2004, v. 23, n. 10, p. 1845, doi. 10.1038/sj.onc.1207307
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- Article
Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09387-4
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- Article
Induction of Lysosomal Membrane Permeabilization Is a Major Event of FTY720-Mediated Non-Apoptotic Cell Death in Human Glioma Cells.
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- Cancers, 2020, v. 12, n. 11, p. 3388, doi. 10.3390/cancers12113388
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- Article
Dexamethasone Inhibits TRAIL-Induced Apoptosis through c-FLIP(L) Upregulation and DR5 Downregulation by GSK3β Activation in Cancer Cells.
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- Cancers, 2020, v. 12, n. 10, p. 2901, doi. 10.3390/cancers12102901
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- Article
Upregulation of DR5 and Downregulation of Survivin by IITZ-01, Lysosomotropic Autophagy Inhibitor, Potentiates TRAIL-Mediated Apoptosis in Renal Cancer Cells via Ubiquitin-Proteasome Pathway.
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- Cancers, 2020, v. 12, n. 9, p. 2363, doi. 10.3390/cancers12092363
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- Article
Flavonoids in Cancer Metastasis.
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- Cancers, 2020, v. 12, n. 6, p. 1498, doi. 10.3390/cancers12061498
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- Article
WP1130 Enhances TRAIL-Induced Apoptosis through USP9X-Dependent miR-708-Mediated Downregulation of c-FLIP.
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- Cancers, 2019, v. 11, n. 3, p. 344, doi. 10.3390/cancers11030344
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- Article
The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice.
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- International Journal of Nanomedicine, 2013, v. 8, p. 147, doi. 10.2147/IJN.S39534
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- Article
Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63085-6
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- Article