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- Title
Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement.
- Authors
Tosun, Ayşe; Serdaroğlu, Gül; Aslan, Mehmet Tayyip; Polat, Muzaffer; Akalın, Taner; Tekgul, Hasan; Gökben, Sarenur
- Abstract
Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He had a rapidly progressive course and died in 7 weeks after the onset of the disease despite steroid and immunosuppressive treatment. The second case (a 14-year-old boy) was presented with myositis complicated with hepatitis. He also had a chronic course of JDM with unfavorable outcome. It appears that the prognosis of patients with severe JDM is related with the degree of autoimmune vasculitis on extra musculocutaneous involvement.
- Subjects
DERMATOMYOSITIS; MUSCULOCUTANEOUS flaps; INTERSTITIAL lung diseases in children; HEPATITIS in children; TOMOGRAPHY; PATIENTS
- Publication
Rheumatology International, 2006, Vol 26, Issue 11, p1040
- ISSN
0172-8172
- Publication type
Article
- DOI
10.1007/s00296-006-0141-4