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- Title
Expansion of large granular lymphocytes following Pseudomonas infection in a patient with adult-onset Still's disease.
- Authors
Tabata, Rie; Tabata, Chiharu; Fukuda, Hiromi; Kotani, Hiroyuki
- Abstract
We report a patient who had a 4-year history of adult-onset Still's disease (AOSD) and showed a prominent increase in large granular lymphocytes (LGL) when she developed severe Pseudomonas conjunctivitis due to Pseudomonas aeruginosa, skin eruptions, liver damage, and abnormal findings in coagulation studies, without any evidence of active viral activation, hemophagocytosis, or malignancies. The increased LGL cells were CD3(+)CD8(+), and disappeared promptly after the administration of antibiotics combined with prednisolone, with subsequent stabilization of her general condition.
- Subjects
STILL'S disease; LYMPHOCYTES; PSEUDOMONAS aeruginosa; PSEUDOMONAS aeruginosa infections; CONJUNCTIVITIS
- Publication
Modern Rheumatology, 2006, Vol 16, Issue 2, p101
- ISSN
1439-7595
- Publication type
Article
- DOI
10.3109/s10165-006-0462-x