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- Title
PHENOTYPIC AND GENOTYPIC DETECTION OF BIOFILM IN STAPHYLOCOCCUS EPIDERMIDIS ISOLATED FROM SOME CLINICAL SPECIMENS IN KERBALAPROVINCE.
- Authors
Al-Janabi, Riyam Ahmed Shehab; Ali, Angham Jasim Mohammed; Al-Saadi, Hassan Ali
- Abstract
Staphylococcus epidermidis, the most frequently isolated coagulase-negative staphylococcus, is the leading cause of infection related to implanted medical devices (IMDs). This is directly related to its capability to establish multilayered, highly structured biofilm on artificial surfaces. At present, conventional systemic therapies using standard antimicrobial agents represent the main strategy to treat and prevent medical device-associated infections. PCR assay was used to detect the presence of icaA gene in the bacterial isolates, and the micro titter plate assay was used to detect the ability for biofilm production. This study was aimed to detect the phenotypic and genotyping of virulence factors of S.epidermidis bacteria isolated from patients with variety infections from different clinical specimens. As a result, the biofilm production ability was strongly associated with the presence of icaA gene in the bacterial isolates.
- Subjects
STAPHYLOCOCCUS epidermidis; PHENOTYPES; BIOFILMS; MICROBIAL virulence; POLYMERASE chain reaction
- Publication
Biochemical & Cellular Archives, 2019, Vol 19, Issue 1, p737
- ISSN
0972-5075
- Publication type
Article
- DOI
10.35124/bca.2019.19.1.737