The article describes a study on the importance of von Hippel-Lindau tumor suppressor protein (pVHL) in building cilia. It references a study by Schermer et al in this same issue. Patients who lack the protein suffer from a profusion of cancers and kidney cysts. Researchers found that loss of pVHL did not increase the speed of the separation of microtubules within kidney cells. pVHL holds onto a protein complex that helps direct cell polarity.