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- Title
Comparison of Lyme Disease in the United States and Europe.
- Authors
Marques, Adriana R.; Strle, Franc; Wormser, Gary P.
- Abstract
Lyme disease, or Lyme borreliosis, is the most common tickborne disease in the United States and Europe. In both locations, Ixodes species ticks transmit the Borrelia burgdorferi sensu lato bacteria species responsible for causing the infection. The diversity of Borrelia species that cause human infection is greater in Europe; the 2 B. burgdorferi s.l. species collectively responsible for most infections in Europe, B. afzelii and B. garinii, are not found in the United States, where most infections are caused by B. burgdorferi sensu stricto. Strain differences seem to explain some of the variation in the clinical manifestations of Lyme disease, which are both minor and substantive, between the United States and Europe. Future studies should attempt to delineate the specific virulence factors of the different species of B. burgdorferi s.l. responsible for these variations in clinical features.
- Subjects
EUROPE; UNITED States; LYME disease; TICK-borne diseases; DISEASE progression; BABESIA; BORRELIA burgdorferi; SPECIES diversity; IXODES; LYME disease diagnosis; GRAM-negative bacteria; TICKS; BACTERIA; ANIMALS
- Publication
Emerging Infectious Diseases, 2021, Vol 27, Issue 8, p2017
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2708.204763