We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Clinical and radiobiological consideration of cyclical hypofractionated radiation therapy also known as QUAD Shot for neglected skin cancer disfiguring the face of a noncompliant patient who was refusing surgery and protracted radiation therapy: case report
- Authors
Whoon Jong Ki; Camphausen, Kevin; In Hye Cho
- Abstract
Although surgery is the mainstay of local treatment for skin cancer, definitive radiation therapy (RT) has been also applied for patients who are unable to tolerate surgery. Definitive RT regimens usually consist of daily treatment for 4-7 weeks. Such protracted daily RT regimens, however, would not be feasible for non-compliant patients or patients who are unable to make multiple daily trips for weeks. Without treatment, however, skin cancers can continuously progress and cause distressing symptoms. A cyclical hypofractionated RT (QUAD Shot: 14 Gy in 4 fractions, twice-daily treatments with 6 hours interval on 2 consecutive days) can be a practical RT regimen for those patients. In this report, we present the successful treatment course of repeated QUAD Shots in a 79-year-old patient with neglected skin cancer that was disfiguring his face yet declined definitive surgery and protracted RT. We also evaluated and compared biologically equivalent doses between QUAD Shots and conventionally fractionated protracted RT regimens.
- Subjects
SKIN cancer; SURGERY; CANCER treatment; PATIENT refusal of treatment; FACE; CANCER radiotherapy
- Publication
Radiation Oncology Journal, 2019, Vol 37, Issue 2, p143
- ISSN
2234-1900
- Publication type
Article
- DOI
10.3857/roj.2019.00248