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- Title
Current approaches and perspectives in human keratinocyte-based gene therapies.
- Authors
Del Rio, M.; Gache, Y.; Jorcano, J. L.; Meneguzzi, G.; Larcher, F.
- Abstract
Inherited and acquired disorders are liable to treatment with somatic gene therapy. The skin, and in particular epidermal cells, are particularly suited to genetic manipulation and follow-up of therapeutic effects. Cutaneous gene therapy may be effective for skin defects and systemic abnormalities. The robust basic and preclinical data available today would support the application of keratinocyte-based gene therapy to patients.
- Subjects
GENE therapy; GENETIC engineering; GENETIC transformation; TISSUE engineering; STEM cells; GENETICS
- Publication
Gene Therapy, 2004, Vol 11, pS57
- ISSN
0969-7128
- Publication type
Article
- DOI
10.1038/sj.gt.3302370