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- Title
Effect of Exogenous Intravenous Administrations of GLP-1 and/or GIP on Circulating Pro-Atrial Natriuretic Peptide in Subjects With Different Stages of Glucose Tolerance.
- Authors
Rudovich, Natalia; Pivovarova, Olga; Gögebakan, Özlem; Sparwasser, Andrea; Doehner, Wolfram; Anker, Stefan D.; Arafat, Ayman M.; Bergmann, Andreas; Nauck, Michael A.; Pfeiffer, Andreas F. H.
- Abstract
The article talks about exogenous intravenous administration of GLP-1 and glucose-dependent insulinotropic peptide (GIP) in patients with type 2 diabetes mellitus (T2DM). Topics include GLP-1's direct interaction with Midregional pro - atrial natriuretic peptide (MR-proANP) among healthy but overweight subjects and the results of the study which shows that pharmacological doses of the GLP-1 and GIP, alone or in combination, does not stimulate ANP secretion.
- Subjects
GLUCAGON-like peptide 1; GASTRIC inhibitory polypeptide; TYPE 2 diabetes treatment; ATRIAL natriuretic peptides; DRUG dosage; PHARMACODYNAMICS
- Publication
Diabetes Care, 2015, Vol 38, Issue 1, pe7
- ISSN
0149-5992
- Publication type
Article
- DOI
10.2337/dc14-1452