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- Title
RELATIONSHIP BETWEEN GENETIC ANOMALIES OF DIFFERENT LEVELS AND DEVIATION IN DERMATOGLYPHIC TRAITS PART 3b: DERMATOGLYPHIC PECULIARITIES OF MALES WITH THE KLINEFELTER'S SYNDROME. MULTIVARIATE ANALYSIS.
- Authors
Kobyliansky, Eugene; Bejerano, Michal; Yakovenko, Konstantin; Katznelson, Mariassa Bat-Miriam
- Abstract
The present study is carried out to evaluate the effect of chromosomal morbidity (82% are 47 XXY and in the remaining cases there is an extra X and/or Y) in males with the Klinefelter's syndrome, based on dermatoglyphic traits and the indices of diversity and asymmetry. The main objective of the present study is to find dermatoglyphic traits and the fluctuating asymmetry and diversity indices which could indicate the developmental instability of the organism. The problem of asymmetry, fluctuating and directional and of the intraindividual diversity of quantitative dermatoglyphic traits is reviewed here as well as illustrated by the data obtained from a sample of the healthy control group of Jews from Israel. In the first part of this paper (Part 3a, 2004), we focused our attention on the data of individual dermatoglyhic traits on digits and palms. The second part (Part 3b) is dedicated to the multivariate analysis in order to make a comparison between the Klinefelter's syndrome and the control healthy individuals based on 79 dermatoglyphic variables for every patient: 28 continuous traits, 9 discrete traits, 11 indices of intraindividual diversity, 15 indices of directional and 16 indices of fluctuating asymmetry. The Klinefelter's Syndrome (KS) was first described by Klinefelter in 1942, and it was shown to be due to the presence of an additional X chromosome in 1959. It is the first human sex chromosome abnormality to be reported. The incidence is about 1 in 1000 male live births, half of all 47, xxy conceptions are lost prenataly. In a combined cytogenetic and molecular investigation of the paternal origin and the meiotic stage of the non-dysfunctional error responsible for the syndrome, it was found that about half of the cases result from errors in paternal meiosis I and one third from errors in maternal meiosis I, and the remaining from errors in Meiosis II, or from the postzygostic mitotic error leading to mosaicism. Maternal age is increased in the...
- Subjects
MULTIVARIATE analysis; CHROMOSOMES; DISEASES; ORGANISMS; KLINEFELTER'S syndrome
- Publication
Papers on Anthropology, 2004, Vol 13, p93
- ISSN
1406-0140
- Publication type
Article