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- Title
BIOPSY CONFIRMATION OF TRANSVAGINAL ULTRASONOGRAPHY RESULTS IN PATIENTS WITH MENOPAUSAL METRORRHAGE.
- Authors
Nurciu, M.; Man, G. M.; Mitrea, Mihaela; Francu, L. L.
- Abstract
The concurrent use of transvaginal ultrasound and histopathological diagnosis in 62 patients with postmenopausal bleeding admitted to the Obstretics and Gynecology Department of Calinesti-Arges Hospital in the interval October 2008 - August 2010, resulted in an overall increase in specificity and sensitivity compared to each technique alone that is a more effective anatomo-clinical diagnosis for the detection of endometrial cancer. The endometrial lesions were diagnosed by histopathological examination in 34 patients (54.8%), in 19 patients by transvaginal ultrasonography, 9 patients been free of endometrial lesions. By the concurrent use of these two methods the specificity was of 73.9%, sensitivity 73/7%, positive predictive value 77.3%, negative predictive value 70% and efficacy 73.8%. Efficacy could be increased to 81% if a threshold value of endometrial thickness of 5 mm as is considered, with a statistically significant difference (p< 0.001). Transvaginal ultrasound allows the detection of pathological endometrial changes in most cases, being a simple, relatively cheap, and non-invasive method that does not require anesthesia is used as a first step in the investigation of patients with postmenopausal bleeding.
- Subjects
DIAGNOSIS of endometrial cancer; BIOPSY; MENOPAUSE; TRANSVAGINAL ultrasonography; DISEASES in women; HEMORRHAGE; CANCER in women
- Publication
Romanian Journal of Functional & Clinical, Macro & Microscopical Anatomy & of Anthropology / Revista Româna de Anatomie Functionala si Clinica, Macro si Microscopica si de Antropologie, 2011, Vol 10, Issue 4, p504
- ISSN
1583-4026
- Publication type
Article