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- Title
Effective Concentration of Lidocaine Plus Fentanyl for Caudal Block in Patients Undergoing Transrectal Ultrasound Guided Prostate Biopsy.
- Authors
Wang, Jinguo; Zhou, Honglan; An, Wei; Wang, Na; Gao, Yang
- Abstract
Objective. This study determined the effective concentration (EC) of lidocaine plus 75 μg fentanyl for caudal block in patients undergoing transrectal ultrasound (TRUS) guided prostate biopsy. Methods. Consecutive male patients scheduled for TRUS guided prostate biopsy were enrolled. The mixed solution for caudal block contained lidocaine and 75 μg fentanyl, in total 20 mL. The concentration of lidocaine was determined using the up-and-down method, starting at 0.8% (a step size of 0.1%). A successful caudal block was defined by no pain perception during biopsy. The EC50 of lidocaine for successful caudal block was calculated and side effects were evaluated. Results. A total of 23 patients were recruited. The EC50 of lidocaine for successful caudal block was 0.53%. Conclusions. Lidocaine of 0.53% combined with 75 μg fentanyl resulted in excellent caudal block in 50% of male patients undergoing transrectal ultrasound guided prostate biopsy.
- Subjects
LIDOCAINE; ENDORECTAL ultrasonography; FENTANYL; PROSTATE biopsy; PROSTATE disease diagnosis; PROSTATE diseases; DRUG side effects; THERAPEUTICS
- Publication
Pain Research & Treatment, 2016, p1
- ISSN
2090-1542
- Publication type
Article
- DOI
10.1155/2016/5862931