We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of Omega-3 on Recurrent Aphthous Stomatitis and Improvement Quality of Life.
- Authors
Hadian, Zahra; Moghadamnia, Ali Akbar; Kazemi, Sohrab; Shirzad, Atena
- Abstract
Objective. Recurrent aphthous stomatitis is one of the most common chronic inflammatory diseases in oral mucosa. Beneficial effects of omega-3 supplements on some inflammatory diseases have been proved. The aim of present study was to evaluate the effect of omega-3 supplements in recurrent aphthous stomatitis management and improve oral health-related quality of life. Methods. In this double-blind clinical trial, 40 patients with minor recurrent aphthous stomatitis were randomly divided into case and control groups. The case group received 1000 mg capsules of omega-3, while the control group received placebo capsules for 6 months. The questionnaires of the ulcer severity score and the chronic oral mucosal disease questionnaire were filled by the patients in three steps, at the baseline session, after 3 months, and after 6 months. The data were analyzed by SPSS 22 software through ANOVA, Mann–Whitney, and chi-square tests. P < 0.05 was considered as significant. Results. In the omega-3 group, the ulcer severity score showed significant reduction by three-month and six-month follow-ups (P < 0.0001 , P < 0.0001 , respectively). The mean score of the chronic oral mucosal disease questionnaire significantly improved by three-month and six-month follow-ups in the omega-3-receiving group. Conclusion. Use of omega-3 oral supplements decreased the severity of aphthous ulcer and improved oral health-related quality of life.
- Subjects
ORAL mucosa diseases; CANKER sores; QUALITY of life; OMEGA-3 fatty acids; DIETARY supplements
- Publication
International Journal of Dentistry, 2021, p1
- ISSN
1687-8728
- Publication type
Article
- DOI
10.1155/2021/6617575