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- Title
Temperature sensitive semi-IPN microspheres from sodium alginate and N-isopropylacrylamide for controlled release of 5-fluorouracil.
- Authors
Mallikarjuna Reddy, K.; Ramesh Babu, V.; Krishna Rao, K. S. V.; Subha, M. C. S.; Chowdoji Rao, K.; Sairam, M.; Aminabhavi, T. M.
- Abstract
The article discusses a study which determined the thermosensitive property of semi-interpenetrating network (IPN) microspheres through water-in-oil emulsification process. Sodium alginate (NaAlg) and N-isopropylacrylamide (NIPAAm) microspheres were characterized by Fourier transform infrared spectroscopy (FTIR) and surface morphology by differential scanning calorimetry (DSC). The dispersion of 5-fluorouracil (5-FU) at the molecular level at 25 and 37 degrees Centigrade is revealed.
- Subjects
ALGINATES; SODIUM; ACRYLAMIDE; FLUOROURACIL; FOURIER transform infrared spectroscopy; CALORIMETRY
- Publication
Journal of Applied Polymer Science, 2008, Vol 107, Issue 5, p2820
- ISSN
0021-8995
- Publication type
Article
- DOI
10.1002/app.27305