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- Title
PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant.
- Authors
Wójtowicz, Agnieszka; Lecompte, T. Doco; Bibert, Stephanie; Manuel, Oriol; Rüeger, Sina; Berger, Christoph; Boggian, Katia; Cusini, Alexia; Garzoni, Christian; Hirsch, Hans; Khanna, Nina; Mueller, Nicolas J.; Meylan, Pascal R.; Pascual, Manuel; van Delden, Christian; Bochud, Pierre-Yves
- Abstract
Donor PTX3 polymorphisms were shown to influence the risk of invasive aspergillosis among hematopoietic stem cell transplant recipients. Here, we show that PTX3 polymorphisms are independent risk factors for invasive mold infections among 1101 solid organ transplant recipients, thereby strengthening their role in mold infection pathogenesis and patients' risk stratification.
- Subjects
ASPERGILLOSIS; PENTRAXINS; GENETIC polymorphisms; HEMATOPOIETIC stem cell transplantation; MOLDS (Fungi); IMMUNOSUPPRESSIVE agents; IMMUNOREGULATION; DISEASE risk factors
- Publication
Clinical Infectious Diseases, 2015, Vol 61, Issue 4, p619
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/civ386