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- Title
Fetal pulmonary maturity: relationship between optical density (650 nm) to the lecithin/sphingomyelin ratio and phosphatidylglycerol in amniotic fluid.
- Authors
Moodley, Sangithan; Liu, James H.; Cherkis, Richard C.; Miller, Richard K.; Allen Merritt, T.; Whalen, Lorraine E.; Moodley, S; Liu, J H; Cherkis, R C; Miller, R K; Merrit, T A; Whalen, L E
- Abstract
An optical density value greater than or equal to 0.15 at A650 n m of amniotic fluid obtained through transabdominal amniocentesis from a high risk obstetrical population, which excluded diabetes mellitus, isoimmunization, and amniotic fluid infection, correlated 98.6% with a mature lecithin to sphingomyelin ratio (L/S) greater than or equal to 2.0% and 41.6% with the presence of phosphatidylglycerol (PG). The corresponding false positive rates were 1.4% and 16.8%, respectively. In 30 infants delivered within 48 h of testing, A650 n m greater than or equal to 0.15 correlated 100% with absence of respiratory distress syndrome. A650 n m is not recommended for Rhesus immunized gestations, diabetic pregnancies and amniotic fluid infection due to a high false positive rate with A650 nm compared to L/S and PG.
- Publication
International Journal of Gynecology & Obstetrics, 1983, Vol 21, Issue 3, p199
- ISSN
0020-7292
- Publication type
journal article
- DOI
10.1016/0020-7292(83)90080-2