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Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 6287, doi. 10.1002/alz.14122
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- Publication type:
- Article
Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00771-3
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- Publication type:
- Article
Pathologic TDP‐43 downregulates myelin gene expression in the monkey brain.
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- Brain Pathology, 2024, v. 34, n. 6, p. 1, doi. 10.1111/bpa.13277
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- Publication type:
- Article
Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease.
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- EMBO Reports, 2020, v. 21, n. 6, p. 1, doi. 10.15252/embr.201949783
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- Publication type:
- Article
A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin.
- Published in:
- Advanced Science, 2023, v. 10, n. 31, p. 1, doi. 10.1002/advs.202301120
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- Publication type:
- Article
A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin (Adv. Sci. 31/2023).
- Published in:
- Advanced Science, 2023, v. 10, n. 31, p. 1, doi. 10.1002/advs.202370210
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- Publication type:
- Article
Differential Activities of the Ubiquitin-Proteasome System in Neurons versus Glia May Account for the Preferential Accumulation of Misfolded Proteins in Neurons.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 49, p. 13285, doi. 10.1523/JNEUROSCI.4393-08.2008
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- Publication type:
- Article
Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 24, p. 6182, doi. 10.1523/JNEUROSCI.0857-08.2008
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- Publication type:
- Article
N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking.
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- Journal of Neuroscience, 2008, v. 28, n. 11, p. 2783, doi. 10.1523/JNEUROSCI.0106-08.2008
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- Publication type:
- Article
Regulation of Intracellular Trafficking of Huntingtin-Associated Protein-1 Is Critical for TrkA Protein Levels and Neurite Outgrowth.
- Published in:
- Journal of Neuroscience, 2006, v. 26, n. 22, p. 6019, doi. 10.1523/JNEUROSCI.1251-06.2006
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- Publication type:
- Article
Huntington aggregates may not predict neuronal death in Huntington's disease.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Expression and Localization of Huntingtin-Associated Protein 1 (HAP1) in the Human Digestive System.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Targeted genome editing in primate embryos.
- Published in:
- Cell Research, 2015, v. 25, n. 7, p. 767, doi. 10.1038/cr.2015.64
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- Publication type:
- Article
Species-dependent neuropathology in transgenic SOD1 pigs.
- Published in:
- Cell Research, 2014, v. 24, n. 4, p. 464, doi. 10.1038/cr.2014.25
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- Publication type:
- Article
Polyglutamine toxicity in non-neuronal cells.
- Published in:
- Cell Research, 2010, v. 20, n. 4, p. 400, doi. 10.1038/cr.2010.32
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- Publication type:
- Article
Toughening Effect of Oxirane‐Tetrahydrofuran Polyether (PEOT) on Blended and Cross‐Linked Nitrocellulose.
- Published in:
- Propellants, Explosives, Pyrotechnics, 2022, v. 47, n. 6, p. 1, doi. 10.1002/prep.202100385
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- Publication type:
- Article
Expression of Mutated Huntingtin Fragment in the Putamen Is Sufficient to Produce Abnormal Movement in Non-human Primates.
- Published in:
- Molecular Therapy, 2007, v. 15, n. 8, p. 1444, doi. 10.1038/sj.mt.6300185
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- Publication type:
- Article
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity.
- Published in:
- Journal of Cell Biology, 2005, v. 171, n. 6, p. 1001, doi. 10.1083/jcb.200508072
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- Publication type:
- Article
Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity.
- Published in:
- Journal of Cell Biology, 2003, v. 163, n. 1, p. 109, doi. 10.1083/jcb.200306038
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- Publication type:
- Article
Ahi1 regulates the nuclear translocation of glucocorticoid receptor to modulate stress response.
- Published in:
- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01305-x
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- Publication type:
- Article
Dynamic Regulation of DNA Methylation and Brain Functions.
- Published in:
- Biology (2079-7737), 2023, v. 12, n. 2, p. 152, doi. 10.3390/biology12020152
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- Publication type:
- Article
Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16318-1
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- Publication type:
- Article
Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14931-8
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- Publication type:
- Article
CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases.
- Published in:
- Frontiers in Molecular Neuroscience, 2016, p. 1, doi. 10.3389/fnmol.2016.00030
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- Publication type:
- Article
Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review.
- Published in:
- Frontiers in Molecular Neuroscience, 2016, p. 1, doi. 10.3389/fnmol.2016.00027
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- Publication type:
- Article
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons.
- Published in:
- EMBO Journal, 2008, v. 27, n. 15, p. 2124, doi. 10.1038/emboj.2008.133
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- Publication type:
- Article
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys.
- Published in:
- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01601-6
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- Publication type:
- Article
Insights into White Matter Defect in Huntington's Disease.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 21, p. 3381, doi. 10.3390/cells11213381
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- Publication type:
- Article
Adenosine A<sub>2A</sub> receptor mediates microglial process retraction.
- Published in:
- Nature Neuroscience, 2009, v. 12, n. 7, p. 872, doi. 10.1038/nn.2341
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- Publication type:
- Article
Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration.
- Published in:
- Nature Neuroscience, 2007, v. 10, n. 12, p. 1519, doi. 10.1038/nn2011
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- Publication type:
- Article
HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice.
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- Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06716-4
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- Publication type:
- Article
New pathogenic insights from large animal models of neurodegenerative diseases.
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- Protein & Cell, 2022, v. 13, n. 10, p. 707, doi. 10.1007/s13238-022-00912-8
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- Publication type:
- Article
Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys.
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- BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-88
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- Publication type:
- Article
Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys.
- Published in:
- 2013
- By:
- Publication type:
- journal article
Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains.
- Published in:
- Acta Neuropathologica, 2019, v. 137, n. 6, p. 919, doi. 10.1007/s00401-019-01979-0
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- Publication type:
- Article
Large animal models for Huntington’s disease research.
- Published in:
- Zoological Research, 2024, v. 45, n. 2, p. 275, doi. 10.24272/j.issn.2095-8137.2023.199
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- Publication type:
- Article
Genetically modified non-human primate models for research on neurodegenerative diseases.
- Published in:
- Zoological Research, 2024, v. 45, n. 2, p. 263, doi. 10.24272/j.issn.2095-8137.2023.197
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- Publication type:
- Article
Comparative analysis of primate and pig cells reveals primate-specific PINK1 expression and phosphorylation.
- Published in:
- Zoological Research, 2024, v. 45, n. 2, p. 242, doi. 10.24272/j.issn.2095-8137.2023.241
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- Publication type:
- Article
A booming field of large animal model research.
- Published in:
- Zoological Research, 2024, v. 45, n. 2, p. 311, doi. 10.24272/j.issn.2095-8137.2024.018
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- Publication type:
- Article
Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin.
- Published in:
- Journal of Cell Biology, 2008, v. 181, n. 5, p. 803, doi. 10.1083/jcb.200710158
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- Publication type:
- Article
Impaired ubiquitin--proteasome system activity in the synapses of Huntington's disease mice.
- Published in:
- Journal of Cell Biology, 2008, v. 180, n. 6, p. 1177, doi. 10.1083/jcb.200709080
- By:
- Publication type:
- Article
Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurologicalphenotypes of Huntington¿s disease mice.
- Published in:
- Molecular Brain, 2010, v. 3, p. 33, doi. 10.1186/1756-6606-3-33
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- Publication type:
- Article
Mutant HTT does not affect glial development but impairs myelination in the early disease stage.
- Published in:
- Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1238306
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- Publication type:
- Article
Transport feasibility of proppant by supercritical carbon dioxide fracturing in reservoir fractures.
- Published in:
- Journal of Hydrodynamics, 2018, v. 30, n. 3, p. 507, doi. 10.1007/s42241-018-0055-0
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- Publication type:
- Article
Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains.
- Published in:
- Cellular & Molecular Life Sciences, 2022, v. 79, n. 11, p. 1, doi. 10.1007/s00018-022-04577-8
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- Publication type:
- Article
Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells.
- Published in:
- Cellular & Molecular Life Sciences, 2012, v. 69, n. 8, p. 1305, doi. 10.1007/s00018-011-0692-8
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- Publication type:
- Article
Association of HAP1 Isoforms with a Unique Cytoplasmic Structure.
- Published in:
- Journal of Neurochemistry, 1998, v. 71, n. 5, p. 2178, doi. 10.1046/j.1471-4159.1998.71052178.x
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- Publication type:
- Article
N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.
- Published in:
- PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006083
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- Publication type:
- Article
Postnatal Loss of Hap1 Reduces Hippocampal Neurogenesis and Causes Adult Depressive-Like Behavior in Mice.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 4, p. 1, doi. 10.1371/journal.pgen.1005175
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- Publication type:
- Article