We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Comparison of Renal Function after Partial Nephrectomy and Radical Nephrectomy for Renal Cell Carcinoma.
- Authors
Miyamoto, Katsutoshi; Inoue, Shogo; Kajiwara, Mitsuru; Teishima, Jun; Matsubara, Akio
- Abstract
Objective: To investigate the time-dependent changes of estimated glomerular filtration rate (eGFR) after radical nephrectomy (RN) and partial nephrectomy (PN) for renal cell carcinoma (RCC) and to determine the risk factors for the new onset of a postoperative eGFR <60 ml/min/1.73 m2. Patients and Methods: We assessed the renal function of 253 RCC patients by using the eGFR, and investigated the time-dependent changes of the eGFR after the operation. Regression models were used to determine risk factors for the new onset of an eGFR of <60 ml/min/1.73 m2 in 211 patients who had at least one month of postoperative follow-up. Results: From the first postoperative day to the 60th postoperative month the eGFR in the RN group was significantly lower than that in the PN group. For patients who had at least 1 month of postoperative follow-up, multivariable analysis revealed that RN (p < 0.001), age (p = 0.028), and maleness (p = 0.013) were risk factors for the postoperative onset of an eGFR <60 ml/min/1.73 m2. Conclusions: Renal function after PN was better than that after RN, and RN was a greater risk factor for the postoperative onset of an eGFR <60 ml/min/ 1.73 m2. Copyright © 2012 S. Karger AG, Basel
- Subjects
RENAL cell carcinoma; NEPHRECTOMY; GLOMERULAR filtration rate; REGRESSION analysis; POSTOPERATIVE period; COMPARATIVE studies; FOLLOW-up studies (Medicine)
- Publication
Urologia Internationalis, 2012, Vol 89, Issue 2, p227
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000339969