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- Title
Drosophila melanogaster embryonic haemocytes: masters of multitasking.
- Authors
Wood, Will; Jacinto, Antonio
- Abstract
Drosophila melanogaster haemocytes constitute the cellular arm of a robust innate immune system in flies. In the adult and larva, these cells operate as the first line of defence against invading microorganisms: they phagocytose pathogens and produce antimicrobial peptides. However, in the sterile environment of the embryo, these important immune functions are largely redundant. Instead, throughout development, embryonic haemocytes are occupied with other tasks: they undergo complex migrations and carry out several non-immune functions that are crucial for successful embryogenesis.
- Subjects
BLOOD cells; DROSOPHILA; FRUIT flies; DROSOPHILA melanogaster; IMMUNE system; PATHOGENIC microorganisms; PEPTIDE antibiotics
- Publication
Nature Reviews Molecular Cell Biology, 2007, Vol 8, Issue 7, p542
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm2202