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- Title
Cell signalling: How mTORC1 senses leucine.
- Authors
Baumann, Kim
- Abstract
The article discusses research being done on cell signalling. It references the article "Sestrin2 is a leucine sensor for the mechanistic target of rapamycin complex 1 (mTORC1) pathway" by R. L. Wolfson and colleagues in the 2015 issue of "Science" journal. Topics mentioned include the report on the function of inhibitor sestrin 2 as a mTORC1 pathway leucine sensor, the performing of an equilibrium binding assay, and the testing of mutant forms of sestrin 2.
- Subjects
CELL communication; LEUCINE; ENZYME inhibitors; BINDING site assay; RAPAMYCIN
- Publication
Nature Reviews Molecular Cell Biology, 2015, Vol 16, Issue 12, p699
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm4088