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- Title
Risk factors for breakthrough COVID‐19 infections in solid organ transplant recipients receiving tixagevimab/cilgavimab for pre‐exposure prophylaxis.
- Authors
Abraham, Dana L.; Lichvar, Alicia B.; Brubaker, Aleah L.; Haste, Nina; Chen, Victor; Abeles, Shira; Aslam, Saima; Yam, Nancy; Horton, Lucy; Chen, Benjamin; Binkin, Nancy; Law, Nancy
- Abstract
This article examines breakthrough COVID-19 infections in solid organ transplant recipients who received Tixagevimab/Cilgavimab (T/C) prophylaxis. The study found that there is limited data on the effect of T/C prophylaxis on breakthrough infections in this population during the omicron variant era. The analysis included 481 adult solid organ transplant recipients who received T/C at the University of California San Diego Health. The study found that breakthrough infections were associated with being further out from transplant and from the last vaccine dose, as well as cyclosporine use and lower prednisone doses. The study provides insights into the risk factors for breakthrough infections in solid organ transplant recipients receiving T/C prophylaxis, but further research is needed.
- Subjects
UNIVERSITY of California, San Francisco; BREAKTHROUGH infections; TRANSPLANTATION of organs, tissues, etc.; PRE-exposure prophylaxis; SARS-CoV-2 Omicron variant; CYCLOSPORINE
- Publication
Transplant Infectious Disease, 2023, Vol 25, Issue 6, p1
- ISSN
1398-2273
- Publication type
Article
- DOI
10.1111/tid.14125