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- Title
Comparison of allergic responses to dust mites in U.K. bakery workers and Swedish farmers.
- Authors
Tee, R. D.; Gordon, D. J.; van Hage-Hamsten, M.; Gordon, S.; Nunn, A. J.; Johansson, S. G. O.; Newman Taylor, A. J.
- Abstract
The IgE RAST response to Dermatophagoides pteronyssinus and four storage mites (Lepidoglyphus destructor, Tyrophagus putrescentiae, Glycyphaghus domesticus, and Acarus siro) was examined in 251 U.K. bakery workers and compared with that previously found in 440 Swedish fanners. Storage mites are found commonly in stored hay and grain so both these groups potentially encounter them in their work. In neither group of workers was a positive RAST(≥ 0.35 PRU) to D. pteronyssinus correlated with a positive RAST to a single storage mite. As in the Swedish farmers, significant though not strong correlations were found in the U.K. bakers between positive RAST responses to G. domesticus and L. destructor and to T. putrescentiae and L. destructor (P < 0.05). Homologous and heteroiogous RAST inhibition studies showed there was low crossreactivity between storage mites and D. pteronyssinus. L. destructor showed the least inhibition by the other antigens, suggesting it possessed the fewest common allergens. The most important difference in the IgE responses between the two groups was the much higher response to D. pteronyssinus in the U.K. bakers, which was not found in the Swedish farmers whose highest IgE response was to L. destructor.
- Subjects
DERMATOPHAGOIDES pteronyssinus; BAKERY employees; MITES; GRAIN; ALLERGENS; FARMERS
- Publication
Clinical & Experimental Allergy, 1992, Vol 22, Issue 2, p233
- ISSN
0954-7894
- Publication type
Article
- DOI
10.1111/j.1365-2222.1992.tb03078.x