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- Title
Effect Of Heat Treatment On Antimicrobial Activity Of Medicinal Plant Extract Against Atcc 25923 Staphylococcus aureus.
- Authors
Francis A. L.; Namasivayam, S. Karthick Raja; Bhuvaneshwari, G.; Thamayanthi, Catherine
- Abstract
Since prehistoric times till the present and most probably in the future, medicinal plants will take the spotlight in the pharmaceutical industry because of their rich important natural sources of antioxidants for novel drugs discovery and development. Plants synthesise several bioactive compounds that exhibit a high antioxidant capacity. Furthermore, because of their anti-inflammatory and antimicrobial properties, these antioxidant compounds that have higher heat stability and plays a vital role in plants by maintaining stress tolerance which have a very high connection to human immune system and health. The main focus of this research is to study the effect of heat treatment on phytochemical constituents and their actions against ATCC 25923 Staphylococcus aureus. The plants (Azadirachta indica, Acalypha indica, Vitex negundo, Aloe vera, Justicia adhatoda, Rosa damascene, and Citrus sinensis) were selected and processed. The selected plant extracts were then subjected to phytochemical screening and anti-microbial studies. After the preliminary screening, a part of the respective plant extracts was tested for the effect of heat treatment on them by phytochemical screening and anti-microbial studies. By comparing the results of both the treated and untreated groups, we were able to conclude that there was no antibacterial activity observed in the treated groups because of the inactivation of the bioactive compounds during the treatment (autoclaving it at 121 °C with 15 psi for 30 min), which was confirmed additionally by repeating a phytochemical test. The compounds that were thermally unstable were inactivated by the effect of the heat on them.
- Subjects
PLANT extracts; HEAT treatment; STAPHYLOCOCCUS aureus; MEDICINAL plants; ANTI-infective agents; ORANGES; NEEM
- Publication
Journal of Pharmaceutical Negative Results, 2023, Vol 14, Issue 3, p390
- ISSN
0976-9234
- Publication type
Article
- DOI
10.47750/pnr.2023.14.03.049