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- Title
Molecular Screening of Extended Spectrum β-lactamases in Klebsiella pneumoniae isolated from Clinical Sources.
- Authors
Jassim, Sawsan Abdulhameed; Hassan, Muthanna Hamid
- Abstract
Klebsiella pneumoniae is a major pathogen responsiple for nosocomial infections in world hospitals. One of the causes for the drug resistance in the Klebsiella pneumoniae is the production of ESBls enzymes. This research documented TEM, SHV, and CTX-M for the first time among Klebsiella pneumoniae in Al-Anbar hospitals of Iraqi. All studied clinical isolates of K. pneumoniae (30) resistant-beta lactam from 100 isolates were collected from different clinicals sources such as (burned, wounds, sputum, and urine samples). The susceptibility to different antibiotics was tested by VITEK-2 system. The bla TEM, SHV, and CTX-M genes were detected by conventional PCR and the result showed 30/30 (100%) strains harbored these genes. This results showed the coexistence of these genes in one strains of K. pneumoniae, while indicated widespread ESBLs in Anbar, Iraq.
- Subjects
KLEBSIELLA pneumoniae; MEDICAL screening; BETA lactamases; NOSOCOMIAL infections; DRUG resistance; TEST systems
- Publication
Journal of Pharmaceutical Negative Results, 2022, Vol 13, p2436
- ISSN
0976-9234
- Publication type
Article
- DOI
10.47750/pnr.2022.13.S06.317