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- Title
Role of 64 slice multidetector computed tomography and angiography to establish relationship between tumor size, aneurysm formation and spontaneous rupture of renal angiomyolipomas: Single center experience.
- Authors
Gandhi, Shruti P.; Pal, Bipin Chandra; Patel, Kajal N.; Sutariya, Harsh; Trivedi, Hargovind L.
- Abstract
Objective: To evaluate the role of computed tomography (CT) angiography using 64 slice multidetector CT scan to establish relationships among tumor size, aneurysm formation, and spontaneous rupture of renal angiomyolipomas (AML). Materials and Methods: Total 27 patients were diagnosed as having renal angiomyolipoma (AML) at institute of kidney disease and research center from June 2008 to June 2015. All patients with renal AML underwent contrast-enhanced CT (CECT) with CT angiography with 64 slice multidetector CT scan. Kidneys were divided into two groups; unruptured and ruptured AML based on CT findings. The single largest lesion in each kidney was evaluated for tumor size on CECT. CT angiography images were evaluated for size of an aneurysm if present; in each group. Tumor and aneurysm sizes were compared, and multiple regression analysis was performed to identify factors affecting the rupture. Results: Total 34 kidneys were found to be affected by AML. Out of which 6 AML were ruptured and remaining 28 were unruptured. If tumor size of 4 cm or larger is used as predictor of rupture; sensitivity 20%, specificity 89%, positive predictive value 83.3%, and negative predictive value 28.5%; and If aneurysm size >5 mm is used as predictor of rupture; sensitivity 75%, specificity 90%, positive predictive value 50%, and negative predictive value 96.4% was found. Conclusion: Tumor size, aneurysm size and tumor multiplicity cannot use as a predictor of spontaneous rupture of the tumor.
- Subjects
COMPUTED tomography; ANGIOGRAPHY; ANEURYSMS; TUMOR growth; KIDNEY diseases; TISSUE wounds
- Publication
Urology Annals, 2016, Vol 8, Issue 2, p173
- ISSN
0974-7796
- Publication type
Article
- DOI
10.4103/0974-7796.172213