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- Title
Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina.
- Authors
Yu-Ming Ju; Guei-Jane Wang; Chun-Yao Chen; Ya-Jing Tsau; Chang-Hung Chou; Tzong-Huei Lee
- Abstract
Lacrymarone (1), a novel diterpenoid, together with seven known compounds 2-8 were isolated from the fermented broth and mycelium of Lacrymaria velutina, an edible fungus collected in Taiwan. The structures of 1-8 were elucidated by analyzing their spectroscopic data. Further biological tests revealed that the co-crystal of 7 and 8 exhibited a moderate inducible nitric oxide synthase (iNOS) inhibitory activity, and with an IC50 value of 59.54 ± 3.74 μM.
- Subjects
TAIWAN; BASIDIOMYCETES; FERMENTATION; MYCELIUM; VELUTINA; DITERPENES; NITRIC oxide
- Publication
Botanical Studies, 2010, Vol 51, Issue 3, p311
- ISSN
1817-406X
- Publication type
Article