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- Title
HEPATOPROTECTIVE ACTIVITY OF PHYLLANTHUS RETICULATUS.
- Authors
Das, Biplab K.; Bepary, Sukumar; Datta, Bidyut K.; Chowdhury, A. K. Azad; Ali, Mohammad Shawkat; Rouf, Abu Shara Shamsur
- Abstract
Two partially purified organic fractions designated by PR1 and PR2 of the fat free ethanol (95%) extract of aerial parts of Phyllanthus reticulatus were tested for the hepatoprotective activity in rats against CCl4-induced liver damage. The rats receiving the fractions showed promising hepatoprotective activity as evident from significant changes of pentobarbital-induced sleeping time, changes in serum levels of sGPT, sGOT, sALP and bilirubin and also from histopathological changes as compared to CCl4-intoxicated rats.
- Subjects
PHYLLANTHUS; RATS; LIVER; PENTOBARBITAL; SERUM; BILIRUBIN; HISTOPATHOLOGY; ALCOHOL; SLEEP
- Publication
Pakistan Journal of Pharmaceutical Sciences, 2008, Vol 21, Issue 4, p333
- ISSN
1011-601X
- Publication type
Article