We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
High-temperature repetitive nerve stimulation in myasthenia gravis.
- Authors
Rutkove, Seward B.; Shefner, Jeremy M.; Wang, Annabel K.; Ronthal, Michael; Raynor, Elizabeth M.; Rutkove, S B; Shefner, J M; Wang, A K; Ronthal, M; Raynor, E M
- Abstract
High temperature enhances the decrement on repetitive nerve stimulation (RNS) in patients with myasthenia gravis (MG). However, the limit of this phenomenon at high temperature is unknown. Three-hertz ulnar RNS was performed in 7 patients with MG at a skin temperature of 32 degrees C and then with the hand in a 44 degrees C water bath. At 32 degrees C, the mean decrement preactivation was 5% (range, 0-24%); after 1 min of exercise, the mean decrement reached a maximum of 11% (range, 1-34%) 2 min postactivation. At a hand temperature of 42 degrees C, the mean decrement preactivation was 17% (range, 0-65%); after exercise, the mean decrement reached a maximum of 29% (range, 5-74%) 1 min postactivation. In 3 subjects, RNS was normal at 32 degrees C, but a definite decrement developed with heating. These findings demonstrate that very high temperature can improve the sensitivity of ulnar RNS for postsynaptic neuromuscular transmission defects.
- Publication
Muscle & Nerve, 1998, Vol 21, Issue 11, p1414
- ISSN
0148-639X
- Publication type
journal article
- DOI
10.1002/(SICI)1097-4598(199811)21:11<1414::AID-MUS8>3.0.CO;2-C