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- Title
Meta analysis on effect of local application of chiorhexidine with scaling and root planing.
- Authors
Lin -Li; Li Xiao-yan; Liang Li -yun; Jiang Xia -jia; Li -Zhe; Pan Ya-ping
- Abstract
PURPOSE: Meta analysis was used to assess the effect of local drug delivery system of chlorhexidine (CHX) as an adjunct to scaling and root planning (SRP) versus SRP alone in patients with chrome periodontitis. METHODS: The selected studies of randomized controlled trials (RCTs) were pooled from six major electronic database up to May, 2009 as CHX plus SRP versus SRP with at least 3 months of follow-up. Several English full texts were hand searched. Outcome measures were probing depth (PD) reduction and clinical attachment level (CAL) gain. RESULTS: Seven studies that met inclusion criteria were entered into the Meta analysis. A significant mean reduction of PD in patients with CHX plus SRP was observed, but there were no significant difference in CAL between the two treatment groups. CONCLUSIONS: Chlorhexidine as an adjunct to SRP could reduce probing depth in the treatment of chronic periodontitis. Supported by Research Project of Education Bureau of Liaoning Province (Grant No.20061021).
- Subjects
META-analysis; DRUG delivery systems; CHLORHEXIDINE; TOOTH roots; PERIODONTITIS; RANDOMIZED controlled trials
- Publication
Shanghai Journal of Stomatology, 2010, Vol 19, Issue 2, p124
- ISSN
1006-7248
- Publication type
Article