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- Title
Molecular Regulation of Angiogenesis in the Skin.
- Authors
Detmar, Michael
- Abstract
The growth of new capillaries from pre-existing blood vessels, generally referred to as angiogenesis, is a complex multi-step process involving extravasation of plasma proteins, degradation of extracellular matrix, endothelial cell migration, proliferation and capillary tube formation. Primary angiogenesis is a prominent feature of developing skin in embryogenesis. In contrast, the adult cutaneous vasculature is normally quiescent, with the possible exception of some angiogenesis related to the early anagen phase of the hair cycle.
- Subjects
NEOVASCULARIZATION; BLOOD vessels; BLOOD proteins; CELL migration; EXTRACELLULAR matrix; SKIN
- Publication
Journal of Investigative Dermatology, 1996, Vol 106, Issue 2, p207
- ISSN
0022-202X
- Publication type
Editorial
- DOI
10.1111/1523-1747.ep12340457