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- Title
Receptors for Innate Pathogen Defence in Insects are Normal Activation Receptors for Specific Immune Responses in Mammals.
- Authors
Möller
- Abstract
The Toll genes code for activation receptors for innate microbial defence in insects and have recently been found to code for the Lps receptor in murine B lymphocytes. In this study, I will present evidence to show that this family of receptors are responsible for induction of specific thymus-independent immune responses in mice. T cells do not possess these pattern-recognizing receptors, but they possess structures capable of delivering activation signals to these receptors on B cells.
- Subjects
CELL receptors; LABORATORY mice; B cells
- Publication
Scandinavian Journal of Immunology, 1999, Vol 50, Issue 4
- ISSN
0300-9475
- Publication type
Article