We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Increased gingival blood vessel density in SLE patients.
- Authors
Alessandro Scardina, Giuseppe; Messina, Pietro
- Abstract
Objective: Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients. Method and Materials: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns. Results: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 ± 3.41) (P < .05). Conclusion: This study showed significant modifications of gingival microcirculation in SLE patients.
- Subjects
ITALY; GINGIVAL hyperplasia; AUTOIMMUNE diseases; BLOOD testing; SYSTEMIC lupus erythematosus; U-statistics; VASCULITIS; VIDEO recording; EQUIPMENT &; supplies; DATA analysis software; DISEASE risk factors
- Publication
Quintessence International, 2012, Vol 43, Issue 6, p511
- ISSN
0033-6572
- Publication type
Article