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- Title
Vanilloid-Like Agents: Potential Therapeutic Targeting of Platelets?
- Authors
Adams, Murray J.; Almaghrabi, Safa Y.; Ahuja, Kiran D. K.; Geraghty, Dominic P.
- Abstract
The article presents an analysis of the mechanisms of involved in platelet aggregation and activation, focusinf on the properties of vanilloids and the receptor, TRPV1. It explores the effects of vanilloids, particularly capsaicinoids, on platelets to determine their potential therapeutic benefits. It suggests that vanilloids appear to modulate the function of platelets.
- Subjects
BLOOD platelet activation; BLOOD platelet aggregation; TRPV cation channels; TRP channels; CARDIOVASCULAR diseases
- Publication
Drug Development Research, 2013, Vol 74, Issue 7, p450
- ISSN
0272-4391
- Publication type
Article
- DOI
10.1002/ddr.21102