We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Familial correlation of bone mineral density, birth data and lifestyle factors among adolescent daughters, mothers and grandmothers.
- Authors
Ohta, Hiroaki; Kuroda, Tatsuhiko; Onoe, Yoshiko; Nakano, Chie; Yoshikata, Remi; Ishitani, Ken; Hashimoto, Kazunori; Kume, Miyoko
- Abstract
This study aimed to clarify the relationship between skeletal or lifestyle factors among Japanese daughter-mother, mother-grandmother and daughter-grandmother pairs. We performed a cross-sectional study in a cohort of Japanese adolescent daughters (12-18 years of age), their mothers (339 pairs) and grandmothers on their mothers' side (34 pairs). Gestational age, birth weight, age at menarche and presence of menarche or menopause were surveyed in the participants. Height, body weight and lumbar 2-4 bone mineral density (BMD) were measured. Dietary intake and current physical activity were assessed by using questionnaires. Gestational age and age at menarche were significantly correlated among daughters, mothers and grandmothers (P < 0.001). BMD was significantly correlated between daughters and mothers (P < 0.001), while it was not significantly correlated between daughters and grandmothers or between mothers and grandmothers. Dietary intake of calcium and vitamin D, and the frequency, duration and intensity of current physical activity were significantly correlated between daughters and mothers (P < 0.05), although no significant correlation was found between daughters and grandmothers, or between mothers and grandmothers. The parameters for exercise indicated a positive correlation for BMD in the daughters and the mothers, but not in the grandmothers. The results suggested that estrogen deficiency decreases familial correlation for BMD after menopause. Achieving high BMD through exercise may be important for prevention of postmenopausal osteoporosis in premenopausal low-height mothers.
- Subjects
JAPAN; LIFESTYLES; CROSS-sectional method; BONE density; ESTROGEN; GESTATIONAL age; QUESTIONNAIRES; DAUGHTERS; MOTHERS; GRANDMOTHERS; OSTEOPOROSIS prevention; DIETARY calcium; COMPARATIVE studies; FAMILIES; LONGITUDINAL method; LUMBAR vertebrae; RESEARCH methodology; MEDICAL cooperation; MENARCHE; MOTOR ability; RESEARCH; VITAMIN D; EVALUATION research; BODY mass index; FETAL development
- Publication
Journal of Bone & Mineral Metabolism, 2010, Vol 28, Issue 6, p690
- ISSN
0914-8779
- Publication type
journal article
- DOI
10.1007/s00774-010-0180-5