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- Title
Two Novel Illudalane Sesquiterpenoids from Pteris semipinnata.
- Authors
Xiong, Yanfen; Yan, Yongxin; Xie, Anqi; Lu, Weiren; Liu, Jianqun; Peng, Caiying; Shu, Jicheng
- Abstract
Two novel illudalane sesquiterpenoids, named as semipterosin D (1) and semipterosode A (2), together with eight known illudalane sesquiterpenoids (3–10), were isolated from the aerial parts of Pteris semipinnata. Their structures were elucidated by HR-ESI-MS, NMR spectral data, CD and literature comparisons. Compound 1 is the first C12 illudalane sesquiterpenoid, and compound 2 is the second report of the C13 illudalane sesquiterpenoid in natural products. Compounds 4–6 and 10 were isolated from this plant for the first time. New compounds were assessed for their anti-inflammatory activity. Compounds 1 and 2 inhibited the NF-κB induction by 26.6% and 43.7%, respectively.
- Subjects
SESQUITERPENES; PTERIS; NATURAL products; ANTI-inflammatory agents; PTERIDACEAE
- Publication
Chemistry of Natural Compounds, 2024, Vol 60, Issue 3, p454
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-024-04350-2