We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Post-operative Management of Pulmonary Arterial Hypertension after Surgical Closure of Hypertensive Ventricular Septal Defect in Pediatrics.
- Authors
Rezk, Moataz E.; Kasab, Ibrahim M.; Aglan, Basem M.; Saleh, Mohammed A.; Abdelrahman, Eman G.; Elshafie, Mahmoud A.
- Abstract
Background: In spite of the great improvement in the intensive care management of cases of left to right shunt with pulmonary hypertension and understanding a lot about path physiology of pulmonary hypertension and the use of recent medications and methods to prevent and treat its hazards, it still has less satisfactory outcome after closure in comparison to cases with lower pulmonary artery pressure. Our objective was to evaluate the use of selective oral pulmonary vasodilators in the postoperative period in comparison to anti-failure measures alone. Results: A retrospective study included 120 patients below two years who underwent surgical closure for hypertensive ventricular septal defect. Patients were divided into two groups each consists of 60 patients. In group I patients received anti-failure drugs only and in group II patients received selective pulmonary vasodilators in addition to anti-failure drugs. The preoperative patients data and echo pressure measurements where comparable among both groups with non-significant difference. The time of ventilation, ICU stay and hospital stay were significantly shorter in group II (p < 0.05). The rates of hypertensive crisis and 30-days mortality were higher in group I but without significant difference (p > 0.05). Conclusions: Pulmonary antihypertensive drugs have an important role in lowering the pulmonary artery pressure and give better results after surgical closure of ventricular septal defect.
- Subjects
PULMONARY arterial hypertension; CRITICAL care medicine; PHYSIOLOGY; VASODILATORS; PULMONARY artery
- Publication
Zagazig University Medical Journal, 2023, Vol 29, Issue 2, p464
- ISSN
1110-1431
- Publication type
Article
- DOI
10.21608/zumj.2021.89415.2309