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- Title
Vertical Transmission of Hepatitis C in Pregnant Women and possible risk factor for perinatal outcome at Zagazig University Hospital.
- Authors
El-Sayed, Gamal Abbas; Mohammed, Mohammed El-Sayed; Shazly, Shereen Attia; Alsonusi, Intesar Khamis
- Abstract
Background: Hepatitis C virus (HCV) considered a serious health problem over the world, which cause chronic liver diseases, cirrhosis, liver failure and hepatocellular carcinoma. In Egypt the prevalence of HCV was 14.7% for positive HCV antibody (Ab) between 15 to 59 years age group during the year 2008, but in the year 2015, there was a significant reduction of in HCV antibody positive and HCV RNA positive individuals (32% and 29% respectively) according to the Egyptian Health Issues Survey (EHIS) and HCV seroprevalence was 10% and 7% viremia between 15 to 59 years age group. Objectives: The aim of this study was to compare the prevalence of HCV RNA positive pregnant women with the general population and discover the possible risk factor for perinatal outcome. Patients & Methods: This cross-sectional study was performed on 187 pregnant women admitted for labour at Zagazig university hospital between May 2018 to December 2018. Results: the results showed that all women in study were comparable as regards mean age with significant association (p=0.001) with increase maternal age, geogravical distribution, socio-economic level, household contact of HCV patient, previous abortion with significant association (p=0.03). The risk factor for HCV infection in study participant varied between visiting dentist, previous blood transfusion without statisyically significant difference. Conclusions: several risk factors for mother-to-child transmission were determined but none are modifiable and there was no interventions available to prevent vertical transmission.
- Subjects
HEPATITIS C treatment; PERINATAL care; UNIVERSITY hospitals; VERTICAL transmission (Communicable diseases); HEPATOCELLULAR carcinoma; CARRIER state (Communicable diseases)
- Publication
Zagazig University Medical Journal, 2022, Vol 28, p249
- ISSN
1110-1431
- Publication type
Article
- DOI
10.21608/zumj.2020.27257.1795