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- Title
Effects of Streptococcus sanguinis Bacteriocin on Deformation, Adhesion Ability, and Young’s Modulus of Candida albicans.
- Authors
Ma, Shengli; Ge, Wenyu; Yan, Yifan; Huang, Xu; Ma, Li; Li, Chunmei; Yu, Shuyang; Chen, Chunxiao
- Abstract
In order to study the thallus changes on microscopic morphology and mechanical properties of Candida albicans antagonized by Streptococcus sanguinis bacteriocin, the adhesion ability and Young’s modulus of thalli and hypha of Candida albicans were measured by the relative measurement method using atomic force microscope’s (AFM) tapping model. The results showed that the average adhesion ability and Young’s modulus of thalli were 7.35±0.77 nN and 7.33±1.29 Mpa, respectively; the average adhesion ability and Young’s modulus of hypha were 9.82±0.39 nN and 4.04±0.76 Mpa, respectively. After being antagonized by Streptococcus sanguinis bacteriocin, the adhesion ability was decreased along with the increasing of deformation in reaction region and Young’s modulus followed the same changes. It could be concluded that the adhesion ability of hypha was greater than thalli, Young’s modulus of hypha was less than thalli, and adhesion ability and Young’s modulus of Candida albicans were decreased significantly after being antagonized by Streptococcus sanguinis bacteriocin.
- Subjects
TISSUE adhesions; CANDIDA albicans; RESEARCH methodology; STREPTOCOCCUS; ENHANCEMENT medicine
- Publication
BioMed Research International, 2017, Vol 2017, p1
- ISSN
2314-6133
- Publication type
Article
- DOI
10.1155/2017/5291486