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- Title
Direct LDL Cholesterol Assay vs. Estimated Equations in Patients With Hypertriglyceridemia or Low LDL Cholesterol Levels.
- Authors
Rodríguez-Domínguez, Jennifer; Piedra-Aguilera, Álvaro; Martínez-Bujidos, María; Malumbres-Serrano, Susana; Morales-Indiano, Cristian; Fernández-Prendes, Carla
- Abstract
This letter to the editor published in the Annals of Laboratory Medicine discusses the measurement of low-density lipoprotein cholesterol (LDL-C) levels and compares different methods for accuracy and speed. The study found that the direct LDL-C assay and Martin-Hopkins equation were the most accurate alternatives to the reference method, particularly in patients with high triglyceride levels. However, for individuals with low LDL-C levels or high triglyceride levels, other equations tended to underestimate LDL-C levels. The study concludes that the direct LDL-C assay is the best choice for individuals with specific lipid profiles.
- Subjects
LDL cholesterol; HYPERTRIGLYCERIDEMIA; BLOOD lipoproteins; BLOOD cholesterol; CLINICAL chemistry
- Publication
Annals of Laboratory Medicine, 2024, Vol 44, Issue 4, p363
- ISSN
2234-3806
- Publication type
Article
- DOI
10.3343/alm.2023.0387