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- Title
Topical finasteride: A potential therapeutic option for hidradenitis suppurativa.
- Authors
Manfredini, Marco; Alma, Antonio; Pongetti, Linda; Sticchi, Alberto; Baschieri, Erica; Farnetani, Francesca; Pellacani, Giovanni
- Abstract
It is possible to recognize the presence of 4 inflammatory nodules in the axillary regions of the first patient (A, B) and the remission of acute inflammation with the persistence of postinflammatory erythema after therapy (C, D). Multiple therapies have been described, including topical, systemic, surgical, and physical treatments.1,5,6 At present, topical HS therapy include cleansers, keratolytic agents, and antibiotics.7 Androgens are implicated in skin physiology and may have a role in HS worsening.8 Consequently, the administration of systemic antiandrogen therapy were described in a small population.5,8 To the best of our knowledge, this is the first study that describes topical antiandrogen therapy in HS. Hidradenitis suppurativa (HS) is a multifactorial disease characterized by the progression of nodules to deep-seated lesions, with subsequent scarring and suppuration.1-4 The exact etiology of HS is still unproven.
- Subjects
FINASTERIDE; THERAPEUTICS; TOPICAL drug administration; BALDNESS
- Publication
Dermatologic Therapy, 2022, Vol 35, Issue 11, p1
- ISSN
1396-0296
- Publication type
Article
- DOI
10.1111/dth.15837