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- Title
An FCER2 polymorphism is associated with increased oral leukotriene receptor antagonists and allergic rhinitis prescribing.
- Authors
Soares, Patricia; Fidler, Katy; Felton, Jessie; Jones, Christina J.; Tavendale, Roger; Hövels, Anke; Bremner, Stephen; Palmer, Colin N. A.; Mukhopadhyay, Somnath
- Abstract
Keywords: asthma; atopic dermatitis; pharmacogenomics; pharmacology; rhinitis EN asthma atopic dermatitis pharmacogenomics pharmacology rhinitis 1089 1092 4 08/03/21 20210801 NES 210801 Key Messages We explored associations between genotype and prescriptions for allergic conditions in the BREATHE cohort. Asthma, atopic dermatitis, pharmacogenomics, pharmacology, rhinitis Of the 927 participants included in the study, 493 (53.2%) reported having eczema, 397 (42.8%) reported having rhinitis, 230 (24.8%) reported having rhinitis and eczema, and 267 (28.8%) reported having neither eczema nor rhinitis. We decided to perform rhinitis-related analysis in the entire sample due to discrepant reporting in the data and add a sensitivity analysis, analysing only children and young adults that reported having rhinitis (see Supplementary Material for more details on the methodology).
- Subjects
LEUKOTRIENE antagonists; ALLERGIC rhinitis; ECZEMA; ATOPY; B cell differentiation; MEDICAL prescriptions
- Publication
Clinical & Experimental Allergy, 2021, Vol 51, Issue 8, p1089
- ISSN
0954-7894
- Publication type
Article
- DOI
10.1111/cea.13958