The article presents a case of a 65-year-old male who was rushed to a hospital due to a 5-year history of gradually enlarging, painless, midline mandibular mass to discuss the honeycomb jaw lesion called ameloblastoma. Other topics include the differential diagnosis of ameloblastoma like odontogenic myxoma, central giant cell granuloma and odontogenic keratocyst, and potential ameloblastoma treatment like marginal or segmental resection.