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- Title
Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents.
- Authors
Grotti Clemente, Ana Paula; Dal Molin Netto, Bárbara; di Piano Ganen, Aline; Tock, Lian; Caranti, Danielle Arisa; de Mello, Marco Túlio; Tufik, Sergio; Dâmaso, Ana R.
- Abstract
Objectives.Thepresent study aimed at determining cut-off points of visceral fat to predictNAFLD and analyzedmetabolic disorders of obese adolescents. Methods. Cross-sectional study involved 165 obese adolescents ranged in age from 15 to 19 years. Glycemia, hepatic transaminases, lipid profile, and insulin resistance were analyzed. Visceral and subcutaneous fat were measured by ultrasound and body composition by plesthysmography. Results. The NAFLD adolescents had significantly higher values for body mass, BMI-for-age, BMI, total fat,waist circumference, and visceral fatwhen compared with non-NAFLD obese adolescents in both genders.Moreover, there were significant positive correlations between visceral fat with the variables BMI-for-age (r = 0.325,), TG (r = 0.277), AST (r = 0.509), ALT (r = 0.519), WC (r = 0.390), and visceral/subcutaneous ratio (r = 0.790) for NAFLD group. Total fat, triglycerides, and visceral fat were the independent predictors to NAFLD. Analysis of the ROC curves revealed cut-off points of visceral fat of 4.47 cmfor girls and 4.21 cmfor boys. Conclusions. The resultsmay suggest that abdominal ultrasonography proceduremay be a safe alternative method of assessing visceral adiposity aiming to be considered to the development of preventive and treatment strategies in obese individuals.This clinial trial is registered with ClinicalTrial.gov (NCT01358773).
- Subjects
OBESITY; VISCERAL pain; FATTY liver; OVERWEIGHT persons; METABOLIC disorders; AMINOTRANSFERASES; CROSS-sectional method; BODY mass index
- Publication
Journal of Nutrition & Metabolism, 2013, p1
- ISSN
2090-0724
- Publication type
Article
- DOI
10.1155/2013/724781