We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Ring transformation and antimicrobial activity of indolyl-substituted 2(3 H)-furanones.
- Authors
Abou-Elmagd, Wael S.I.; EL-Ziaty, Ahmed K.; Abdalha, Abdelaal A.
- Abstract
A variety of heterocycles of synthetic and biological importance were prepared from 3-(indol-3-yl-methylene)-5-phenyl-2(3 H)-furanone ( 1) and its hydrazide 2. Compounds 1 and 2 were used for the construction of pyridazin-3(4 H)-ones 4 and 6; 1,3,4-oxadiazoles 7, 8, and 10; and 1,2,4 -triazoles 12, 14, and 15, all bearing a 3-indolyl moiety. The antimicrobial activities of the synthesized compounds were examined against six types of bacteria and two types of fungi.
- Subjects
FURANONES; HETEROCYCLIC compounds; PYRIDAZINES; PYRAZON; OXADIAZOLES
- Publication
Heterocyclic Communications, 2015, Vol 21, Issue 3, p179
- ISSN
0793-0283
- Publication type
Article
- DOI
10.1515/hc-2015-0008