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- Title
Spinal Cystic Echinococcosis – A Systematic Analysis and Review of the Literature: Part 2. Treatment, Follow-up and Outcome.
- Authors
Neumayr, Andreas; Tamarozzi, Francesca; Goblirsch, Sam; Blum, Johannes; Brunetti, Enrico
- Abstract
Bone involvement in human cystic echinococcosis (CE) is rare, but affects the spine in approximately 50% of cases. Despite significant advances in diagnostic imaging techniques, surgical treatment and introduction of pharmacological therapy, spinal echinococcosis remains associated with a high degree of morbidity, disability and mortality. We systematically reviewed the published literature of the last five decades to update and summarize the currently existing data on treatment, follow-up and outcome of spinal CE. Author Summary: Spinal cystic echinococcosis (CE) is a rare but malignant form of a truly neglected tropical disease. Despite modern diagnostic imaging techniques, the advances in surgery over the last decades and the availability of pharmacological therapy, the clinical management of spinal CE cases remains a challenge for the treating physician. Ten years after the last extensive review on the topic was published by Pamir et al. (Spinal Cord, 2002), we aim to provide clinicians with a systematic review and comprehensive update on spinal CE to help them deal with the often very complex clinical management of these patients. By systematically reviewing all published case reports and case series of spinal CE from 1965 until now, we summarized and analyzed the existing data on treatment, follow-up, and outcome of the disease and discuss the findings in light of the existing data.
- Subjects
ECHINOCOCCOSIS; TROPICAL medicine; SPINAL cord; DIAGNOSTIC imaging; MEDICAL personnel
- Publication
PLoS Neglected Tropical Diseases, 2013, Vol 7, Issue 9, p1
- ISSN
1935-2727
- Publication type
Article
- DOI
10.1371/journal.pntd.0002458