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- Title
Diet First, Then Medication for Hypercholesterolemia.
- Authors
Anderson, James W.
- Abstract
Editorial. The findings of Jenkins and colleagues indicate that intensive dietary therapy might be as effective in reducing cholesterol levels as the starting dosage of a 3-hydroxy-3methylglutaryl coenzyme A reductase inhibitor (statin) drug. The authors report that the statin and dietary portfolio treatment groups had about a 30% reduction in low-density lipoprotein cholesterol (LDL-C) compared with an 8% decrease in the control group. Individuals with statin intolerance can develop nonspecific musculoskeletal complaints without a change in serum creatinine kinase. Intensive nutrition management needs soy protein, soluble fiber, and plant sterols added to the diet recommended by the American Heart Association patients with dyslipidemia. There are several caveats to consider before recommending this diet for the general population.
- Subjects
HYPERLIPIDEMIA; STATINS (Cardiovascular agents); NUTRITION; SOY proteins; LOW density lipoproteins; DRUG side effects; CHOLESTEROL
- Publication
JAMA: Journal of the American Medical Association, 2003, Vol 290, Issue 4, p531
- ISSN
0098-7484
- Publication type
Editorial
- DOI
10.1001/jama.290.4.531